2,6-Dichloro-9-(2′,3′,5′-tri-O-acetyl-β-D-ribofuranosyl)-9H-purine

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2,6-Di­chloro-9-(2′,3′,5′-tri-O-acetyl-β-d-ribo­furanos­yl)-9H-purine

The title synthetic analog of purine nucleosides, C16H16Cl2N4O7, has its acetyl-ated β-furan-ose ring in a 3'β-envelope conformation, with the corresponding C atom deviating by 0.602 (5) Å from the rest of the ring. The planar part of the furan-ose ring forms a dihedral angle of 65.0 (1)° with the mean plane of the purine bicycle. In the crystal, mol-ecules form a three-dimensional network thro...

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Synthesis and Enzymic Hydrolysis of Acylated Adenosine Derivatives

Various derivatives of adenosine were prepared by acylation of adenosine (6-amino-9-(bD-ribofuranosyl)purine (1) with different molar equivalents of acetic anhydride and/or pivaloyl chloride in pyridine. Compounds 6-acetylamino-9-[(2,3,5-tri-O-acetyl)-b-Dribofuranosyl]purine (3), 6-amino-9-[(2,3,5-tri-O-acetyl)-b-D-ribofuranosyl]purine (4), and 6-pivaloylamino-9-[(2,3,5-tri-O-pivaloyl)-b-D-ribo...

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ژورنال

عنوان ژورنال: Acta Crystallographica Section E Structure Reports Online

سال: 2014

ISSN: 1600-5368

DOI: 10.1107/s1600536813034521